Polysaccharides from <i>Holothuria leucospilota</i> Relieve Loperamide-Induced Constipation Symptoms in Mice

Polysaccharides from <i>Holothuria leucospilota</i> Relieve Loperamide-Induced Constipation Symptoms in Mice

A vital bioactive component of marine resources is <i>Holothuria leucospilota</i> polysaccharides (HLP). This study examined whether HLP could regulate intestinal flora to treat loperamide-induced constipation. Constipated mice showed signs of prolonged defecation (up by 60.79 min) and a...

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Bibliographic Details
Main Authors: Ziqi Wang, Yali Shi, Shiyu Zeng, Yuanping Zheng, Huaijie Wang, Haihui Liao, Jie Song, Xinyue Zhang, Jun Cao, Chuan Li
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Holothuria leucospilota</i> polysaccharides
constipation
hormone
short-chain fatty acid
gut microbiota
Online Access:https://www.mdpi.com/1422-0067/24/3/2553

Internet

https://www.mdpi.com/1422-0067/24/3/2553

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