Bioreactor as the root cause of the “manganese effect” during Aspergillus niger citric acid fermentations

Bioreactor as the root cause of the “manganese effect” during Aspergillus niger citric acid fermentations

High-yield citric acid production by the filamentous Ascomycete fungus Aspergillus niger requires a combination of extreme nutritional conditions, of which maintaining a low manganese (II) ion concentration (<5 μg L−1) is a key feature. Technical-scale production of citric acid predominantly...

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Bibliographic Details
Main Authors: Erzsébet Fekete, Vivien Bíró, Alexandra Márton, István Bakondi-Kovács, Zoltán Németh, Erzsébet Sándor, Béla Kovács, István Fábián, Christian P. Kubicek, Adrian Tsang, Levente Karaffa
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Aspergillus niger
manganese ions
citric acid
stainless steel
metal ions leaching
fungal morphology
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.935902/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2022.935902/full

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