Bioreactor as the root cause of the “manganese effect” during Aspergillus niger citric acid fermentations
High-yield citric acid production by the filamentous Ascomycete fungus Aspergillus niger requires a combination of extreme nutritional conditions, of which maintaining a low manganese (II) ion concentration (<5 μg L−1) is a key feature. Technical-scale production of citric acid predominantly...
Main Authors: | Erzsébet Fekete, Vivien Bíró, Alexandra Márton, István Bakondi-Kovács, Zoltán Németh, Erzsébet Sándor, Béla Kovács, István Fábián, Christian P. Kubicek, Adrian Tsang, Levente Karaffa |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-08-01
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Series: | Frontiers in Bioengineering and Biotechnology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2022.935902/full |
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