Cortactin Modulates Lung Endothelial Apoptosis Induced by Cigarette Smoke

Cortactin Modulates Lung Endothelial Apoptosis Induced by Cigarette Smoke

Cigarette smoke (CS) is the primary cause of Chronic Obstructive Pulmonary Disease (COPD), and an important pathophysiologic event in COPD is CS-induced apoptosis in lung endothelial cells (EC). Cortactin (CTTN) is a cytoskeletal actin-binding regulatory protein with modulation by Src-mediated tyros...

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Bibliographic Details
Main Authors: Mounica Bandela, Eleftheria Letsiou, Viswanathan Natarajan, Lorraine B. Ware, Joe G. N. Garcia, Sunit Singla, Steven M. Dudek
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cells
Subjects:
COPD
lung injury
e-cigarette
mitochondrial ROS
endothelium
cytoskeleton
Online Access:https://www.mdpi.com/2073-4409/10/11/2869

Internet

https://www.mdpi.com/2073-4409/10/11/2869

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