In vivo and in vitro analysis of age-associated changes and somatic cellular senescence in renal epithelial cells.

In vivo and in vitro analysis of age-associated changes and somatic cellular senescence in renal epithelial cells.

Acute kidney injury is a major clinical problem and advanced age is associated with ineffective renal regeneration and poor functional outcome. Data from kidney injury models suggest that a loss of tubular epithelial proliferation contributes to a decrease in renal repair capacity with aging, but ag...

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Bibliographic Details
Main Authors: Birgit Berkenkamp, Nathan Susnik, Arpita Baisantry, Inna Kuznetsova, Christoph Jacobi, Inga Sörensen-Zender, Verena Broecker, Hermann Haller, Anette Melk, Roland Schmitt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3913727?pdf=render

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http://europepmc.org/articles/PMC3913727?pdf=render

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