Identification of novel DNA methylation inhibitors via a two-component reporter gene system
<p>Abstract</p> <p>Background</p> <p>Targeting abnormal DNA methylation represents a therapeutically relevant strategy for cancer treatment as demonstrated by the US Food and Drug Administration approval of the DNA methyltransferase inhibitors azacytidine and 5-aza-2...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-01-01
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Series: | Journal of Biomedical Science |
Online Access: | http://www.jbiomedsci.com/content/18/1/3 |