Enhanced gastric residence time of acyclovir by floating raft formulation using box-behnken design
This research paper reports enhancing Acyclovir's gastric residence time by implementing a raft-forming drug delivery system. Because acyclovir is a narrow absorption window drug, it has a poor bioavailability of 10–20 % and a short half-life (t1/2) of 2.5 h. The guar gum and GMS-based floating...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-01-01
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| Series: | Heliyon |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024003323 |