P53 Mutation at Codon 249 is Uncommon in Neonatal Kotb Disease Biliary Atresia

Background: Hepatocellular carcinoma (HCC) is known to result from aflatoxin B1 that induces p53 mutation at codon 249. Aflatoxins are also known to cause The Kotb disease Biliary atresia (BA) variant which is characterized by congenital aflatoxicosis B1 in neonates with null glutathione S transfera...

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Bibliographic Details
Main Authors: Magd A. Kotb, Ayda K. Kelany, Sherif Shehata, Gamal El Tagy, Sherif Kaddah, Nahla I. Sabry, Ahmed A. Elhaddad, Radwa Shamma
Format: Article
Language:English
Published: Cairo University, Faculty of Medicine, Department of Pediatrics 2024-01-01
Series:Pediatric Sciences Journal
Subjects:
Online Access:https://cupsj.journals.ekb.eg/article_328321_e60521cc961646904663b2f7ab980f73.pdf