Targeting DNA Repair and Chromatin Crosstalk in Cancer Therapy

Targeting DNA Repair and Chromatin Crosstalk in Cancer Therapy

Aberrant DNA repair pathways that underlie developmental diseases and cancers are potential targets for therapeutic intervention. Targeting DNA repair signal effectors, modulators and checkpoint proteins, and utilizing the synthetic lethality phenomena has led to seminal discoveries. Efforts to effi...

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Bibliographic Details
Main Authors: Danielle P. Johnson, Mahesh B. Chandrasekharan, Marie Dutreix, Srividya Bhaskara
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cancers
Subjects:
DNA repair
cancer therapy
repair inhibition
histone deacetylases
Online Access:https://www.mdpi.com/2072-6694/13/3/381

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https://www.mdpi.com/2072-6694/13/3/381

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