Persistent firing in LEC III neurons is differentially modulated by learning and aging

Whether and how persistent firing in lateral entorhinal cortex layer III (LEC III) supports temporal associative learning is still unknown. In this study, persistent firing was evoked in vitro from LEC III neurons from young and aged rats that were behaviorally naive or trained on trace eyeblink con...

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Bibliographic Details
Main Authors: Carmen Lin, Venus N Sherathiya, M Matthew Oh, John F Disterhoft
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-07-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/56816