Postpartum and non-postpartum depression: a population-based matched case-control study comparing polygenic risk scores for severe mental disorders

Abstract It remains inconclusive whether postpartum depression (PPD) and depression with onset outside the postpartum period (MDD) are genetically distinct disorders. We aimed to investigate whether polygenic risk scores (PGSs) for major mental disorders differ between PPD cases and MDD cases in a n...

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Bibliographic Details
Main Authors: Trine Munk-Olsen, Arianna Di Florio, Kathrine B. Madsen, Clara Albiñana, Merete L. Mægbæk, Veerle Bergink, Vibe G. Frøkjær, Esben Agerbo, Bjarni J. Vilhjálmsson, Thomas Werge, Merete Nordentoft, David M. Hougaard, Anders D. Børglum, Ole Mors, Preben Bo Mortensen, Xiaoqin Liu
Format: Article
Language:English
Published: Nature Publishing Group 2023-11-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-023-02649-2