20-HETE Participates in Intracerebral Hemorrhage-Induced Acute Injury by Promoting Cell Ferroptosis

20-HETE Participates in Intracerebral Hemorrhage-Induced Acute Injury by Promoting Cell Ferroptosis

Intracerebral hemorrhage (ICH) is a highly fatal type of stroke that leads to various types of neuronal death. Recently, ferroptosis, a form of cell death resulting from iron-dependent lipid peroxide accumulation, was observed in a mouse ICH model. N-hydroxy-N′-(4-n-butyl-2-methylphenyl)-formamidine...

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Bibliographic Details
Main Authors: Ranran Han, Jieru Wan, Xiaoning Han, Honglei Ren, John R. Falck, Sailu Munnuri, Zeng-Jin Yang, Raymond C. Koehler
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Neurology
Subjects:
20-hydroxyeicosatetraenoic acid
intracerebral hemorrhage
ferroptosis
glutathione peroxidase
lipid peroxide
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2021.763419/full

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https://www.frontiersin.org/articles/10.3389/fneur.2021.763419/full

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