Endothelial glycocalyx sensitivity to chemical and mechanical sub-endothelial substrate properties

Glycocalyx (GCX) is a carbohydrate-rich structure that coats the surface of endothelial cells (ECs) and lines the blood vessel lumen. Mechanical perturbations in the vascular environment, such as blood vessel stiffness, can be transduced and sent to ECs through mechanosensors such as GCX. Adverse st...

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Bibliographic Details
Main Authors: Mohammad Hamrangsekachaee, Ke Wen, Narges Yazdani, Rebecca K. Willits, Sidi A. Bencherif, Eno E. Ebong
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1250348/full