A Novel Three-Gene Score as a Predictive Biomarker for Pathologically Complete Response after Neoadjuvant Chemotherapy in Triple-Negative Breast Cancer

A Novel Three-Gene Score as a Predictive Biomarker for Pathologically Complete Response after Neoadjuvant Chemotherapy in Triple-Negative Breast Cancer

Although triple-negative breast cancer (TNBC) typically responds better to neoadjuvant chemotherapy (NAC) compared to the other subtypes, a pathological complete response (pCR) is achieved in less than half of the cases. We established a novel three-gene score using genes based on the E2F target gen...

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Bibliographic Details
Main Authors: Masanori Oshi, Fernando A. Angarita, Yoshihisa Tokumaru, Li Yan, Ryusei Matsuyama, Itaru Endo, Kazuaki Takabe
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cancers
Subjects:
three gene
predictive biomarker
prognosis
neoadjuvant chemotherapy
triple-negative breast cancer
tumor immune microenvironment
Online Access:https://www.mdpi.com/2072-6694/13/10/2401

Internet

https://www.mdpi.com/2072-6694/13/10/2401

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