Disease‐modifying effects of ganglioside GM1 in Huntington's disease models

Disease‐modifying effects of ganglioside GM1 in Huntington's disease models

Abstract Huntington's disease (HD) is a progressive neurodegenerative disorder characterized by motor, cognitive and psychiatric problems. Previous studies indicated that levels of brain gangliosides are lower than normal in HD models and that administration of exogenous ganglioside GM1 correct...

Full description

Bibliographic Details
Main Authors: Melanie Alpaugh, Danny Galleguillos, Juan Forero, Luis Carlos Morales, Sebastian W Lackey, Preeti Kar, Alba Di Pardo, Andrew Holt, Bradley J Kerr, Kathryn G Todd, Glen B Baker, Karim Fouad, Simonetta Sipione
Format: Article
Language:English
Published: Springer Nature 2017-10-01
Series:EMBO Molecular Medicine
Subjects:
behaviour
gangliosides
HD mouse models
huntingtin
neuroprotection
Online Access:https://doi.org/10.15252/emmm.201707763

Internet

https://doi.org/10.15252/emmm.201707763

Similar Items