Prevalence of Germline <em>BRCA1/2</em> Variants in Ashkenazi and Non-Ashkenazi Prostate Cancer Populations: A Systematic Review and Meta-Analysis

Prevalence of Germline <em>BRCA1/2</em> Variants in Ashkenazi and Non-Ashkenazi Prostate Cancer Populations: A Systematic Review and Meta-Analysis

Background and aims: International guidelines recommend testing <i>BRCA2</i> in men with prostate cancer, due to the presence of a strong association with this gene. Some ethnicities present disparities in genetic distribution for the relation with specific founder variants. Ashkenazi Je...

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Bibliographic Details
Main Authors: Antonio Cioffi, Ottavio De Cobelli, Paolo Veronesi, Carlo La Vecchia, Patrick Maisonneuve, Giovanni Corso
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Cancers
Subjects:
prostate cancer
<i>BRCA1</i> mutations
<i>BRCA2</i> mutations
Ashkenazi
meta-analysis
Online Access:https://www.mdpi.com/2072-6694/15/1/306

Internet

https://www.mdpi.com/2072-6694/15/1/306

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