Histone deacetylase inhibitors inhibit lung adenocarcinoma metastasis via HDAC2/YY1 mediated downregulation of Cdh1
Abstract Metastasis is a leading cause of mortality in patients with lung adenocarcinoma. Histone deacetylases have emerged as promising targets for anti-tumor drugs, with histone deacetylase inhibitors (HDACi) being an active area of research. However, the precise mechanisms by which HDACi inhibits...
Main Authors: | , , , , , , , , |
---|---|
פורמט: | Article |
שפה: | English |
יצא לאור: |
Nature Portfolio
2023-07-01
|
סדרה: | Scientific Reports |
גישה מקוונת: | https://doi.org/10.1038/s41598-023-38848-6 |