Ultra-high-performance liquid chromatography for the determination of exenatide in monkey plasma by tandem quadrupole mass spectrometry

A highly sensitive ultra-high-performance liquid chromatographicâtandem mass spectrometry (UPLC/MS/MS) method was developed for the quantification of the synthetic peptide drug of exenatide in monkey plasma. Sample preparation was carried out by solid-phase extraction (SPE), and bivalirudin was used...

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Bibliographic Details
Main Authors: Jin-Feng Zhang, Chun-Jie Sha, Yu Sun, Yun-Yun Gai, Ji-Ye Sun, Jiang-Bin Han, Xin Shao, Chun-Na Sha, You-Xin Li, Wan-Hui Liu
Format: Article
Language:English
Published: Elsevier 2013-08-01
Series:Journal of Pharmaceutical Analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177912001487