Effects of different obesogenic diets on joint integrity, inflammation and intermediate monocyte levels in a rat groove model of osteoarthritis

Introduction: Obesogenic diets aggravate osteoarthritis (OA) by inducing low-grade systemic inflammation, and diet composition may affect OA severity. Here, we investigated the effect of diet on joint damage and inflammation in an OA rat model.Methods: Wistar-Han rats (n = 24) were fed a chow, a hig...

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Bibliographic Details
Main Authors: K. Warmink, J. L. Rios, D. R. van Valkengoed, P. Vinod, N. M. Korthagen, H. Weinans
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1211972/full