Chromatin conformation of human oral epithelium can identify orofacial cleft missing functional variants

Chromatin conformation of human oral epithelium can identify orofacial cleft missing functional variants

Abstract Genome-wide association studies (GWASs) are the most widely used method to identify genetic risk loci associated with orofacial clefts (OFC). However, despite the increasing size of cohort, GWASs are still insufficient to detect all the heritability, suggesting there are more associations u...

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Bibliographic Details
Main Authors: Yao Xiao, Shengbo Jiao, Miao He, Da Lin, Huanyan Zuo, Jiahao Han, Yonghua Sun, Gang Cao, Zhi Chen, Huan Liu
Format: Article
Language:English
Published: Nature Publishing Group 2022-08-01
Series:International Journal of Oral Science
Online Access:https://doi.org/10.1038/s41368-022-00194-0

Internet

https://doi.org/10.1038/s41368-022-00194-0

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