ROR2 receptor promotes the migration of osteosarcoma cells in response to Wnt5a
Abstract Background We have reported that the phosphatidylinositol-3 kinase (PI3K)/Akt/RhoA signaling pathway mediates Wnt5a-induced cell migration of osteosarcoma cells. However, the specific receptors responding to Wnt5a ligand remain poorly defined in osteosarcoma metastasis. Methods Wound healin...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-11-01
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Series: | Cancer Cell International |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12935-017-0482-y |