ROR2 receptor promotes the migration of osteosarcoma cells in response to Wnt5a

Abstract Background We have reported that the phosphatidylinositol-3 kinase (PI3K)/Akt/RhoA signaling pathway mediates Wnt5a-induced cell migration of osteosarcoma cells. However, the specific receptors responding to Wnt5a ligand remain poorly defined in osteosarcoma metastasis. Methods Wound healin...

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Bibliographic Details
Main Authors: Bin Dai, Ting Yan, Ailiang Zhang
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Cancer Cell International
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12935-017-0482-y