Thromboxane Modulates Endothelial Permeability

The study tests the role of thromboxane in modulating microvascular permeability in vitro. Cultured monolayers of bovine aortic endothelial cells were challenged with the thromboxane (Tx) mimic U46619. This led to disassembly of actin microfilaments, cell rounding, border retraction and interendothe...

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Bibliographic Details
Main Authors: J. M. Klausner, S. Abu-Abid, J. S. Alexander, R. Hanshke-Mineau, G. Goldman, N. Morel, C. R. Valeri, D. Shepro, H. B. Hechtman
Format: Article
Language:English
Published: Hindawi Limited 1994-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/S0962935194000190