Targeted plasma metabolomics combined with machine learning for the diagnosis of severe acute respiratory syndrome virus type 2

Targeted plasma metabolomics combined with machine learning for the diagnosis of severe acute respiratory syndrome virus type 2

IntroductionThe routine clinical diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is largely restricted to real-time reverse transcription quantitative PCR (RT-qPCR), and tests that detect SARS-CoV-2 nucleocapsid antigen. Given the diagnostic delay and suboptimal sensitivity...

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Bibliographic Details
Main Authors: Anthony T. Le, Manhong Wu, Afraz Khan, Nicholas Phillips, Pranav Rajpurkar, Megan Garland, Kayla Magid, Mamdouh Sibai, ChunHong Huang, Malaya K. Sahoo, Raffick Bowen, Tina M. Cowan, Benjamin A. Pinsky, Catherine A. Hogan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Microbiology
Subjects:
plasma
metabolomics
amino acids
SARS-CoV-2
COVID-19
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.1059289/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.1059289/full

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