A 3D Cell Death Assay to Quantitatively Determine Ferroptosis in Spheroids

The failure of drug efficacy in clinical trials remains a big issue in cancer research. This is largely due to the limitations of two-dimensional (2D) cell cultures, the most used tool in drug screening. Nowadays, three-dimensional (3D) cultures, including spheroids, are acknowledged to be a better...

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Bibliographic Details
Main Authors: Robin Demuynck, Iuliia Efimova, Abraham Lin, Heidi Declercq, Dmitri V. Krysko
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/3/703