Specific targeting of the NRF2/β-TrCP axis promotes beneficial effects in NASH

Specific targeting of the NRF2/β-TrCP axis promotes beneficial effects in NASH

Non-alcoholic steatohepatitis (NASH) is a common chronic liver disease that compromises liver function, for which there is not a specifically approved medicine. Recent research has identified transcription factor NRF2 as a potential therapeutic target. However, current NRF2 activators, designed to i...

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Bibliographic Details
Main Authors: Raquel Fernández-Ginés, José Antonio Encinar, Maribel Escoll, Daniel Carnicero-Senabre, José Jiménez-Villegas, Ángel J. García-Yagüe, Águeda González-Rodríguez, Irma Garcia-Martinez, Ángela M Valverde, Ana I. Rojo, Antonio Cuadrado
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Redox Biology
Subjects:
NRF2
β-TrCP
NASH
Fibrosis
Online Access:http://www.sciencedirect.com/science/article/pii/S221323172400003X

Internet

http://www.sciencedirect.com/science/article/pii/S221323172400003X

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