Identification of Conformational B-cell Epitopes in Diphtheria Toxin at Varying Temperatures Using Molecular Dynamics Simulations

The changes in temperature levels can potentially affect the toxins in terms of stability and immunological properties via alteration of their structures. Diphtheria Toxin (DT) is highly considered by scientists since its mechanism of action is similar to those of most bacterial toxins, such as botu...

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Bibliographic Details
Main Authors: S. Ghaderi, M. R. Bozorgmehr, M. Ahmadi, Sh. Tarahomjoo
Format: Article
Language:English
Published: Razi Vaccine and Serum Research Institute 2021-01-01
Series:Archives of Razi Institute
Subjects:
Online Access:https://archrazi.areeo.ac.ir/article_121516_3c9e365bc87285cfda86e34ea3e4d955.pdf