Evolution of Antibiotic Resistance in Surrogates of Francisella tularensis (LVS and Francisella novicida): Effects on Biofilm Formation and Fitness

Evolution of Antibiotic Resistance in Surrogates of Francisella tularensis (LVS and Francisella novicida): Effects on Biofilm Formation and Fitness

Francisella tularensis, the causative agent of tularemia, is capable of causing disease in a multitude of mammals and remains a formidable human pathogen due to a high morbidity, low infectious dose, lack of a FDA approved vaccine, and ease of aerosolization. For these reasons, there is concern over...

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Bibliographic Details
Main Authors: Fabrice V. Biot, Beth A. Bachert, Kevin D. Mlynek, Ronald G. Toothman, Galina I. Koroleva, Sean P. Lovett, Christopher P. Klimko, Gustavo F. Palacios, Christopher K. Cote, Jason T. Ladner, Joel A. Bozue
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Microbiology
Subjects:
Francisella
Francisella novicida
LVS
antimicrobial resistance
streptomycin
ciprofloxacin
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2020.593542/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2020.593542/full

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