A pharmacodynamic investigation into the efficacy of osteoprotegerin during aseptic inflammation
Background: Osteoprotegerin (OPG), as an osteoclast antagonist, limits mineralised tissue resorption under physiological conditions. Previous work investigating OPG in a rat periodontal ligament (PDL) ankylosis model found no inhibitory effect on osteoclasts when OPG was administered at a dosage of...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Sciendo
2012-11-01
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Series: | Australasian Orthodontic Journal |
Online Access: | https://doi.org/10.2478/aoj-2012-0020 |