Utilizing venous occlusion plethysmography to assess vascular effects: A study with buloxibutid, an angiotensin II type 2 receptor agonist

Abstract Buloxibutid (also known as C21) is a potent and selective angiotensin II type 2 receptor (AT2R) agonist, in development for oral treatment of fibrotic lung disease. This phase I, open‐label, pharmacodynamic study investigated vascular effects of buloxibutid in five healthy male volunteers....

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Bibliographic Details
Main Authors: Erik Rein‐Hedin, Folke Sjöberg, Cecilia Ganslandt, Johan Skoog, Helene Zachrisson, Thomas Bengtsson, Carl‐Johan Dalsgaard
Format: Article
Language:English
Published: Wiley 2024-02-01
Series:Clinical and Translational Science
Online Access:https://doi.org/10.1111/cts.13735