Neuroprotective effect of acid-sensing ion channel inhibitor psalmotoxin-1 after hypoxia–ischemia in newborn piglet striatum

Neuroprotective effect of acid-sensing ion channel inhibitor psalmotoxin-1 after hypoxia–ischemia in newborn piglet striatum

Na+,Ca2+-permeable acid-sensing ion channel 1a (ASIC1a) is involved in the pathophysiologic process of adult focal brain ischemia. However, little is known about its role in the pathogenesis of global cerebral ischemia or newborn hypoxia–ischemia (H–I). Here, using a newborn piglet model of asphyxia...

Full description

Bibliographic Details
Main Authors: Zeng-Jin Yang, Xinli Ni, Erin L. Carter, Kathleen Kibler, Lee J. Martin, Raymond C. Koehler
Format: Article
Language:English
Published: Elsevier 2011-08-01
Series:Neurobiology of Disease
Subjects:
Acid-sensing ion channel
Hypoxia–ischemia
Newborn
Neuroprotection
Striatum
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996111001355

Internet

http://www.sciencedirect.com/science/article/pii/S0969996111001355

Similar Items