Role of pericytes in the development of cerebral cavernous malformations

Role of pericytes in the development of cerebral cavernous malformations

Summary: Cerebral cavernous malformation (CCM) is caused by loss-of-function mutations in CCM1, CCM2, or CCM3 genes of endothelial cells. It is characterized by pericyte deficiency. However, the role of pericytes in CCMs is not yet clarified. We found pericytes in Cdh5CreERT2;Ccm1fl/fl (Ccm1ECKO) mi...

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Bibliographic Details
Main Authors: Zifeng Dai, Jingwei Li, Ying Li, Rui Wang, Huili Yan, Ziyu Xiong, Shiting Wu, Xi Yang, Dongbo Lu, Dongdong Zhang, Guofu Li, Yuwen Wang, Chunyang Men, Wenzhong Du, Xiangjian Zheng, Changbin Shi
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:iScience
Subjects:
Neuroscience
Neuroanatomy
Clinical neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222019149

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http://www.sciencedirect.com/science/article/pii/S2589004222019149

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