The identification of lymphocyte-like cells and lymphoid-related genes in amphioxus indicates the twilight for the emergence of adaptive immune system.

The identification of lymphocyte-like cells and lymphoid-related genes in amphioxus indicates the twilight for the emergence of adaptive immune system.

To seek evidence of a primitive adaptive immune system (AIS) before vertebrate, we examined whether lymphocytes or lymphocyte-like cells and the related molecules participating in the lymphocyte function existed in amphioxus. Anatomical analysis by electron microscopy revealed the presence of lympho...

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Bibliographic Details
Main Authors: Gonghua Huang, Xiaojin Xie, Yan Han, Lifei Fan, Jie Chen, Chunyan Mou, Lei Guo, Hui Liu, Qinfen Zhang, Shangwu Chen, Meiling Dong, Jianzhong Liu, Anlong Xu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1784065?pdf=render

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http://europepmc.org/articles/PMC1784065?pdf=render

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