Lipid-Mediated In Vivo Gene Transfer Replaces the Loss of Choline Acetyltransferase Activity after Unilateral Fimbria-Fornix Aspiration
In Alzheimer's disease cholinergic neurons degenerate, resulting in loss of hippocampal acetylcholine. The fimbria-fornix aspiration is a well-known animal model mimicking hippocampal cholinergic deficiency. The aim of the present study was to use in vivo lipid-mediated gene transfer to introdu...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2001-11-01
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| Series: | Cell Transplantation |
| Online Access: | https://doi.org/10.3727/000000001783986233 |