HIV DNA reservoir increases risk for cognitive disorders in cART-naïve patients.

HIV DNA reservoir increases risk for cognitive disorders in cART-naïve patients.

Cognitive impairment remains frequent in HIV, despite combination antiretroviral therapy (cART). Leading theories implicate peripheral monocyte HIV DNA reservoirs as a mechanism for spread of the virus to the brain. These reservoirs remain present despite cART. The objective of this study was to det...

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Bibliographic Details
Main Authors: Victor G Valcour, Jintanat Ananworanich, Melissa Agsalda, Napapon Sailasuta, Thep Chalermchai, Alexandra Schuetz, Cecilia Shikuma, Chin-Yuan Liang, Supunee Jirajariyavej, Pasiri Sithinamsuwan, Somporn Tipsuk, David B Clifford, Robert Paul, James L K Fletcher, Mary A Marovich, Bonnie M Slike, Victor DeGruttola, Bruce Shiramizu, SEARCH 011 Protocol Team
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3729685?pdf=render

Internet

http://europepmc.org/articles/PMC3729685?pdf=render

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