Improving cardiac differentiation of human pluripotent stem cells by targeting ferroptosis

Generation of cardiomyocytes from human pluripotent stem cells (hPSCs) is of high interest for disease modelling and regenerative medicine. hPSCs can provide an unlimited source of patient-specific cardiomyocytes that are otherwise difficult to obtain from individuals. Moreover, the low proliferatio...

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Bibliographic Details
Main Authors: Jeffrey Aalders, Laurens Léger, Behrouz Hassannia, Vera Goossens, Tom Vanden Berghe, Jolanda van Hengel
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Regenerative Therapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320424000191