Synthesis of sulfur karrikin bioisosteres as potential neuroprotectives

The only known sulfur-containing karrikin, 3-methyl-2H-thiopyrano[3,4-b]furan-2-one, has been recently identified as an extremely efficient neuroprotective butenolide. Herein, we report the targeted synthesis of this compound as well as new synthetic protocols toward a class of compounds derived fro...

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Bibliographic Details
Main Authors: Martin Pošta, Václav Zima, Lenka Poštová Slavětínská, Marika Matoušová, Petr Beier
Format: Article
Language:English
Published: Beilstein-Institut 2022-05-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.18.57