PTHrP intracrine actions divergently influence breast cancer growth through p27 and LIFR
Abstract The role of parathyroid hormone (PTH)-related protein (PTHrP) in breast cancer remains controversial, with reports of PTHrP inhibiting or promoting primary tumor growth in preclinical studies. Here, we provide insight into these conflicting findings by assessing the role of specific biologi...
Main Authors: | , , , , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2024-02-01
|
Series: | Breast Cancer Research |
Online Access: | https://doi.org/10.1186/s13058-024-01791-z |