PTHrP intracrine actions divergently influence breast cancer growth through p27 and LIFR

Abstract The role of parathyroid hormone (PTH)-related protein (PTHrP) in breast cancer remains controversial, with reports of PTHrP inhibiting or promoting primary tumor growth in preclinical studies. Here, we provide insight into these conflicting findings by assessing the role of specific biologi...

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Bibliographic Details
Main Authors: Courtney M. Edwards, Jeremy F. Kane, Jailyn A. Smith, Déja M. Grant, Jasmine A. Johnson, Maria A. Hernandez Diaz, Lawrence A. Vecchi, Kai M. Bracey, Tolu N. Omokehinde, Joseph R. Fontana, Breelyn A. Karno, Halee T. Scott, Carolina J. Vogel, Jonathan W. Lowery, T. John Martin, Rachelle W. Johnson
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Breast Cancer Research
Online Access:https://doi.org/10.1186/s13058-024-01791-z

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