PTHrP intracrine actions divergently influence breast cancer growth through p27 and LIFR
Abstract The role of parathyroid hormone (PTH)-related protein (PTHrP) in breast cancer remains controversial, with reports of PTHrP inhibiting or promoting primary tumor growth in preclinical studies. Here, we provide insight into these conflicting findings by assessing the role of specific biologi...
Main Authors: | Courtney M. Edwards, Jeremy F. Kane, Jailyn A. Smith, Déja M. Grant, Jasmine A. Johnson, Maria A. Hernandez Diaz, Lawrence A. Vecchi, Kai M. Bracey, Tolu N. Omokehinde, Joseph R. Fontana, Breelyn A. Karno, Halee T. Scott, Carolina J. Vogel, Jonathan W. Lowery, T. John Martin, Rachelle W. Johnson |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2024-02-01
|
Series: | Breast Cancer Research |
Online Access: | https://doi.org/10.1186/s13058-024-01791-z |
Similar Items
-
Re-Evaluating the Role of PTHrP in Breast Cancer
by: Jeremy F. Kane, et al.
Published: (2023-05-01) -
PTH/PTHrP activity and the programming of skeletal development in utero.
by: Tobias, J, et al.
Published: (2004) -
Recurrent Pleural Effusions and Elevated PTHrP: An Unusual Case of Sarcoidosis
by: Atchayaa Gunasekharan, et al.
Published: (2020-11-01) -
Cranial Base Synchondrosis Lacks PTHrP-Expressing Column-Forming Chondrocytes
by: Shawn A. Hallett, et al.
Published: (2022-07-01) -
PTHrP Modulates the Proliferation and Osteogenic Differentiation of Craniofacial Fibrous Dysplasia-Derived BMSCs
by: Lihang Shen, et al.
Published: (2023-04-01)