B Cells Isolated from Individuals Who Do Not Respond to the HBV Vaccine Are Characterized by Higher DNA Methylation-Estimated Aging Compared to Responders

B Cells Isolated from Individuals Who Do Not Respond to the HBV Vaccine Are Characterized by Higher DNA Methylation-Estimated Aging Compared to Responders

Healthcare workers (HCWs) are a high-risk group for hepatitis B virus (HBV) infection. Notably, about 5–10% of the general population does not respond to the HBV vaccination. In this study, we aimed to investigate DNA methylation (DNAm) in order to estimate the biological age of B cells from HCW of...

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Bibliographic Details
Main Authors: Katarzyna Malgorzata Kwiatkowska, Simona Anticoli, Stefano Salvioli, Luciano Calzari, Davide Gentilini, Christian Albano, Reparata Rosa Di Prinzio, Salvatore Zaffina, Rita Carsetti, Anna Ruggieri, Paolo Garagnani
Format: Article
Language:English
Published: MDPI AG 2024-08-01
Series:Vaccines
Subjects:
hepatitis B
vaccine
health care workers
sex
immune response
B lymphocytes
Online Access:https://www.mdpi.com/2076-393X/12/8/880

Internet

https://www.mdpi.com/2076-393X/12/8/880

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