Alternatively activated lung alveolar and interstitial macrophages promote fungal growth

Summary: How lung macrophages, especially interstitial macrophages (IMs), respond to invading pathogens remains elusive. Here, we show that mice exhibited a rapid and substantial expansion of macrophages, especially CX3CR1+ IMs, in the lung following infection with Cryptococcus neoformans, a pathoge...

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Bibliographic Details
Main Authors: Ashley B. Strickland, Yanli Chen, Donglei Sun, Meiqing Shi
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223007940