Formation of three types of glucuronides of 6-hydroxy bile acids by rat liver microsomes.

The glucuronidation of 6-hydroxylated bile acids by rat liver microsomes was studied in vitro; for comparison, several major bile acids lacking a hydroxyl group in position 6 were also investigated. The highest reaction rates were found for lithocholic and deoxycholic acid (10.2 +/- 0.2 and 7.3 +/-...

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Bibliographic Details
Main Authors: P Zimniak, A Radominska, M Zimniak, R Lester
Format: Article
Language:English
Published: Elsevier 1988-02-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520385503