Development of Facile and Simple Processes for the Heterogeneous Pd-Catalyzed Ligand-Free Continuous-Flow Suzuki–Miyaura Coupling

Development of Facile and Simple Processes for the Heterogeneous Pd-Catalyzed Ligand-Free Continuous-Flow Suzuki–Miyaura Coupling

The Suzuki–Miyaura coupling reaction is one of the most widely utilized C–C bond forming methods to create (hetero)biaryl scaffolds. The continuous-flow reaction using heterogeneous catalyst-packed cartridges is a practical and efficient synthetic method to replace batch-type reactions. A continuous...

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Bibliographic Details
Main Authors: Tsuyoshi Yamada, Jing Jiang, Naoya Ito, Kwihwan Park, Hayato Masuda, Chikara Furugen, Moeka Ishida, Seiya Ōtori, Hironao Sajiki
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Catalysts
Subjects:
Suzuki–Miyaura coupling
palladium
continuous-flow reaction
ligand-free
chelate resin
aromatic chloride
Online Access:https://www.mdpi.com/2073-4344/10/10/1209

Internet

https://www.mdpi.com/2073-4344/10/10/1209

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