UGT1A1 and UGT1A9 Are Responsible for Phase II Metabolism of Tectorigenin and Irigenin In Vitro

UGT1A1 and UGT1A9 Are Responsible for Phase II Metabolism of Tectorigenin and Irigenin In Vitro

Tectorigenin and irigenin are biologically active isoflavones of <i>Belamcanda chinensis</i> (L.) DC. Previous studies indicated that both compounds could be metabolized in vivo; however, the kinetic parameters of enzymes involved in the metabolization of tectorigenin and irigenin have n...

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Bibliographic Details
Main Authors: Ji Li, Zhangyao Xu, Jifeng Gu
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Molecules
Subjects:
tectorigenin
irigenin
glucuronidation
human liver microsomes
response factor method
Online Access:https://www.mdpi.com/1420-3049/27/13/4104

Internet

https://www.mdpi.com/1420-3049/27/13/4104

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