Thymopoiesis in Pre- and Post-Hematopoietic Stem Cell Transplantation

Thymopoiesis in Pre- and Post-Hematopoietic Stem Cell Transplantation

Hematopoietic stem cell transplantation (HSCT) is an important therapeutic option for some hematological diseases. However, patients who undergo HSCT acquire a state of immunodeficiency that causes significant mortality. Reconstitution of thymic function is needed to support the immune system. One w...

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Bibliographic Details
Main Authors: Luis Klaus A. da Rocha, Samar Freschi de Barros, Francine Bandeira, Alexia Bollini, Lucia Helena de A. Testa, Anderson João Simione, Marina de O. e Souza, Lilian P. Zanetti, Leila Cibele S. de Oliveira, Ana Claúdia F. dos Santos, Mair Pedro de Souza, Vergílio Antônio R. Colturado, Jorge Kalil, Clarisse M. Machado, Luiza Guilherme
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Immunology
Subjects:
T-cell receptor excision circles
T-cell receptor gene
autologous hematopoietic stem cell transplantation
allogeneic hematopoietic stem cell transplantation
malignant hematological diseases
immune reconstitution
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01889/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01889/full

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