Glucose-6-Phosphate Dehydrogenase Deficiency and Neonatal Hyperbilirubinemia: Insights on Pathophysiology, Diagnosis, and Gene Variants in Disease Heterogeneity

Glucose-6-Phosphate Dehydrogenase Deficiency and Neonatal Hyperbilirubinemia: Insights on Pathophysiology, Diagnosis, and Gene Variants in Disease Heterogeneity

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a prevalent condition worldwide and is caused by loss-of-function mutations in the G6PD gene. Individuals with deficiency are more susceptible to oxidative stress which leads to the classical, acute hemolytic anemia (favism). However, G6PD defic...

Full description

Bibliographic Details
Main Authors: Heng Yang Lee, Azlin Ithnin, Raja Zahratul Azma, Ainoon Othman, Armindo Salvador, Fook Choe Cheah
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Pediatrics
Subjects:
molecular screening
bilirubin
favism
hemolytic anemia
neonatal jaundice
peroxiredoxin 2
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2022.875877/full

Internet

https://www.frontiersin.org/articles/10.3389/fped.2022.875877/full

Similar Items