Mucosal-Associated Invariant T Cells Are Depleted and Exhibit Altered Chemokine Receptor Expression and Elevated Granulocyte Macrophage-Colony Stimulating Factor Production During End-Stage Renal Disease

Mucosal-Associated Invariant T Cells Are Depleted and Exhibit Altered Chemokine Receptor Expression and Elevated Granulocyte Macrophage-Colony Stimulating Factor Production During End-Stage Renal Disease

BackgroundEnd-stage renal disease (ESRD) is associated with an increased susceptibility to infectious diseases, including infection with Mycobacterium tuberculosis (Mtb). Mucosal-associated invariant T (MAIT) cells recognize vitamin B metabolites produced by many bacterial species, including Mtb, an...

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Bibliographic Details
Main Authors: Jennifer A. Juno, Jillian L. M. Waruk, Kathleen M. Wragg, Christine Mesa, Carmen Lopez, Joe Bueti, Stephen J. Kent, T. Blake Ball, Sandra A. Kiazyk
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Immunology
Subjects:
end-stage renal disease
mucosal associated invariant T cells
latent tuberculosis
inflammation
granulocyte macrophage-colony stimulating factor
CD161
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01076/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01076/full

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