Biological significance of GPCR heteromerization in the neuro-endocrine system

Clustering of proteins in higher order complexes is a common theme in biology and profoundly influences protein function. The idea that seven-transmembrane spanning G protein-coupled receptors (GPCRs) might form dimers or higher order oligomeric complexes has been formulated more than 20 years ago....

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Bibliographic Details
Main Authors: Ralf eJockers, Maud eKamal
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-02-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2011.00002/full