Regulator of G Protein Signaling 2 Facilitates Uterine Artery Adaptation During Pregnancy in Mice

Regulator of G Protein Signaling 2 Facilitates Uterine Artery Adaptation During Pregnancy in Mice

Background Decreased uterine blood flow is known to contribute to pregnancy complications such as gestational hypertension and preeclampsia. Previously, we showed that the loss of regulator of G protein signaling 2 (RGS2), a GTPase activating protein for Gq/11 and Gi/o class G proteins, decreases ut...

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Bibliographic Details
Main Authors: Jennifer N. Koch, Shelby A. Dahlen, Elizabeth A. Owens, Patrick Osei‐Owusu
Format: Article
Language:English
Published: Wiley 2019-05-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
animal model
G protein–coupled receptor signaling
knockout mice
pregnancy and postpartum
RGS proteins
uterine blood flow
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.118.010917

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.118.010917

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