Mytoxin B and Myrothecine A Induce Apoptosis in Human Hepatocarcinoma Cell Line SMMC-7721 via PI3K/Akt Signaling Pathway

Mytoxin B and Myrothecine A Induce Apoptosis in Human Hepatocarcinoma Cell Line SMMC-7721 via PI3K/Akt Signaling Pathway

Trichothecene macrolides comprise a class of valuable leading compounds in developing anticancer drugs, however, there are few reports concerning their anticancer mechanisms, especially the anticancer mechanism of the 10,13-cyclotrichothecane derivatives that are found mainly in symbiotic fungi. In...

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Bibliographic Details
Main Authors: Huiliang Song, Yi Fu, Dan Wan, Wenjing Xia, Fengwei Lyu, Lijun Liu, Li Shen
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Molecules
Subjects:
trichothecene macrolide
SMMC-7721 cells
anticancer mechanism
apoptosis
PI3K/Akt signaling pathway
Online Access:https://www.mdpi.com/1420-3049/24/12/2291

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https://www.mdpi.com/1420-3049/24/12/2291

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